• Argentinian beats No 9 seed 3-6, 4-6, 6-3, 6-4, 6-4

• Fritz had three break points for chance to serve for match

As his last, desperate backhand soared far past the baseline inside Arthur Ashe Stadium, Taylor Fritz instantly held his face in his hands, unable to hide the agony of squandering such a great opportunity.

For much of his afternoon, Fritz was cruising. He had established a two set against Francisco Cerúndolo before breaking serve in the opening game of the third. One unfocused service game was enough to shift the momentum and once Fritz had lost control, he spent another two hours failing to retrieve it. His US Open ended with an excruciating 3-6, 4-6, 6-3, 6-4, 6-4 third-round defeat by a courageous Cerúndolo.

• Fiery Diamond League comments partially walked back

• On Hocker: ‘Cole and I talked it through after the race’

The double Olympic champion Jakob Ingebrigtsen has issued a part-apology for calling his rivals “losers” and a “bunch of cowards” after a spicy men’s 1500m Diamond League final on Friday.

However, Ingebrigtsen has continued to maintain that he was still right to accuse the Olympic 1500m champion Cole Hocker of cowardice – because he asked for a strong pace and swapped in his own pacemaker only to then hide behind others in the race.

Taylor Fritz and Flavio Cobolli lost from winning positions, Madison Keys collapsed from 5-0 up in the final set, but Coco Gauff, Iga Swiatek and Mirra Andreeva reached the last 16

Last night Serena and Venus Williams – with their combined age of 456 - blew a five-point lead in the deciding tie-break as their return to the grand slam doubles stage ended in defeat, 6-3, 6-7 (6), 7-6 (7) against Chan Hao-ching and Maya Joint. Serena must be sick of the sight of Joint – given her singles comeback was also halted by the Australian in the Wimbledon first round this summer – but having come so close to victory in both matches, she may well be encouraged enough to continue. Serena and Venus chose not to do a post-match media conference last night – so it’s not clear what their next plans are.

A big cheer on Grandstand – despite the fact Zheng is facing an American – as she holds at the start of the second set. Anisimova is still a break down, 3-2, against Potapova, while Taylor Fritz – the pick of the American men in the first week - is warming up on Arthur Ashe against Francisco Cerundolo, the 24th seed from Argentina.

A new study offers more evidence that America’s biggest sport produces life-altering head trauma. The NFL will never turn itself off, so it’s on fans to do so

As a new NFL season begins this Wednesday, the danger of America’s most-watched sport has never been more clear.

A new and widely circulated study published in the British Medical Journal examined the donated brains of former NFL players who died between 2016 and 2021 and compared them with the overall number of players who died during that period. Of the 235 donated brains in that period, 215 had evidence of the degenerative brain condition chronic traumatic encephalopathy (CTE). That group of 215 comprised 24.5% of the former players who died during that period in total. Given the finding, the study’s authors estimate that the prevalence of CTE among players who died in that period was at minimum 24.5% to a maximum of 97.7%, with the actual rate likely somewhere in between.

Nathan Kalman-Lamb is Associate Professor of Sociology at the University of New Brunswick. Derek Silva is Associate Professor of Sociology and Criminology at King’s University College at Western University.

In the US, you can call or text the National Suicide Prevention Lifeline on 988, chat on 988lifeline.org, or text HOME to 741741 to connect with a crisis counselor. In the UK and Ireland, Samaritans can be contacted on freephone 116 123, or email jo@samaritans.org or jo@samaritans.ie. In Australia, the crisis support service Lifeline is 13 11 14. Other international helplines can be found at befrienders.org

• Knyba wins unanimous decision after dropping Ruiz

• Former champion struggles badly after 762-day layoff

• Ruiz, 36, insists another title run remains possible

Andy Ruiz Jr’s comeback bid was left in tatters on Friday night after the former unified heavyweight champion was knocked down and picked apart in a sobering unanimous-decision defeat to Damian Knyba in Newark, New Jersey.

Knyba won by scores of 117-110 and 114-113 twice, handing Ruiz the third defeat of his professional career and dealing a devastating blow to his hopes of becoming a two-time champion in boxing’s prestige division. The baffling pair of 114-113 cards flattered Ruiz considerably and bore little relation to the mostly one-way traffic that unfolded. (The Guardian had it 117-110.)

• American duo lose 6-3, 6-7(6), 7-6(7) to Maya Joint and Chan Hao-ching

• Serena and Venus crash out of women’s doubles in first round

In the end, after so much toil and admirable fight, defeat came swiftly for one of the greatest doubles teams to ever share a tennis court. Upon their return to prime time in New York, Venus and Serena Williams fought desperately to overturn the various deficits they found themselves in over three hours inside a thunderous Arthur Ashe Stadium.

They came close. The Williams sisters had clawed their way back into the match after trailing a 1-4 in their final set against Chan Hao-ching and Maya Joint, and they established a 5-0 lead in the third set tie-break. Just as they appeared to be on the verge of victory, they were brushed aside, losing 6-3, 6-7 (6), 7-6 (7) in the first round of the US Open.