FDA officials approve first-of-a-kind pill called daraxonrasib to fight one of the deadliest types of cancer

The US Food and Drug Administration (FDA) approved a groundbreaking new drug for the most common form of pancreatic cancer, offering US patients a more effective treatment against one of the deadliest types of the disease.

FDA officials gave expedited approval to the first-of-a-kind pill, called daraxonrasib, that blocks a mutated protein that fuels tumor growth in more than 90% of pancreatic cancer cases. It’s an approach that has eluded drugmakers for decades.

New findings further call into question scientific judgment of current health leaders in the Trump administration

A French researcher whose work was praised by Donald Trump and Dr Mehmet Oz during the Covid-19 pandemic published hundreds of papers with “substantial” ethical and legal concerns, according to a new analysis.

An international team of scientists found concerns in 853 articles published by the Institut Hospitalo-Universitaire Méditerranée Infection, or the IHU, hundreds more than previously flagged by past investigations into work at the large research hospital. Of those, institute founder Didier Raoult was listed as co-author on 758 of them, according to one of the researchers behind the new analysis.

Despite the recent hearings in Congress, we seem to be even further from the goal of understanding Covid-19’s origin’s than we have ever been

As a microbiologist and infectious disease clinician, it has been tough to watch the recent devolution of public discourse on Covid-19 origins. It has been especially difficult for me to read the comments of Anthony Fauci about the origins debate in his now-public diary. And it has been painful to watch the televised spectacle hosted by the US senator Rand Paul on 29 July involving a hostile interrogation of Fauci.

Despite many early pleas, including my own, for a dispassionate, objective assessment of what we know, don’t know and need to know about Covid-19 origins, we seem to be even further from this goal now than we have ever been – plagued by politicization, polarization and illogical thinking.

David Relman is a professor of medicine and microbiology at Stanford University. He was an inaugural member of the US National Science Advisory Board for Biosecurity and president of the Infectious Diseases Society of America